Adenosine

Description :

Adenosine has uses as both a diagnostic and therapeutic agent. Adenosine’s use as a pharmacological drug works through receptors called purinergic adenosine receptors found throughout the body. As a diagnostic agent, adenosine can be utilized in myocardial perfusion stress imaging due to its vasodilatory effects.

• Adenine Base: Adenosine contains the adenine base, a purine with a double-ring structure composed of a six-membered and a five-membered ring fused together.
• Ribose Sugar: Adenine is attached to ribose, a five-carbon sugar. This ribose is a part of the nucleoside structure, with adenine linked to it through a β-N9-glycosidic bond.
• Vasodilation: Adenosine promotes vasodilation (widening of blood vessels), which can help regulate blood flow and reduce blood pressure.
• Inflammation and Immune Response: It modulates immune responses and has anti-inflammatory effects. Adenosine can suppress the activation of various immune cells, making it important in managing inflammation and autoimmunity.
• Heart Rate: Adenosine can influence heart rate and cardiac conduction. It is used in medicine to manage certain types of arrhythmias (abnormal heart rhythms) due to its ability to slow down the heart rate and affect electrical conduction in the heart.