Topiramate

Description :

Sihauli Chemical sourcing supplying API, Active pharmaceutical ingredients intermediates, global generics, Pharma Raw Materials, industrial & Specialty Chemicals. our offices at USA, UK, CANADA, AUSTRALIA. generics, Pharma Raw Materials.

• Chemical Formula: C12H21NO8S
• Molecular Weight: 339.37 g/mol
• IUPAC Name: 2,3:4,5-Bis-O-(1-methylethylidene)-D-mannitol sulfate
• GABAergic Activity: Enhances the activity of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain, which helps stabilize neuronal activity.
• Glutamate Receptor Antagonism: Inhibits certain types of glutamate receptors, which are excitatory neurotransmitters, thus reducing excessive neuronal firing.
• Voltage-Gated Ion Channels: Modulates voltage-gated sodium and calcium channels, which helps to prevent neuronal firing and spread of seizure activity.
• Carbonic Anhydrase Inhibition: It also inhibits carbonic anhydrase, an enzyme involved in acid-base balance, which contributes to its therapeutic effects.