Solifenacin Succinate

Description :

Sihauli Chemical is established in 1998 with the purpose of serving the emergent pharmaceutical sector in India and international market. Sihauli has come a long way from being just a chemicals supplier to a big renowned API, Pharmaceutical Intermediate, Nutraceuticals , Herbal Extracts, Industrial Chemicals, and Solvents for manufacturing , supplying, sourcing and marketing company.

• Chemical Formula: C23H26N2O3
• Molecular Weight: 362.47 g/mol
• IUPAC Name: 1-azabicyclo[2.2.2]octan-3-yl (R)-2-[(2,2,2-trifluoroethoxy)methyl]phenyl ketone succinate
• Receptor Binding: It selectively binds to and blocks the muscarinic receptors (particularly M3 receptors) in the bladder.
• Bladder Relaxation: This action reduces the contractility of the detrusor muscle (the muscle responsible for bladder contraction), leading to decreased urinary urgency and frequency.
• Solifenacin succinate is an effective treatment for managing overactive bladder symptoms by targeting muscarinic receptors to reduce bladder contractions. It is typically well-tolerated but can cause side effects such as dry mouth and constipation.