Ondansetron Hydrochloride

Description :

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• Chemical Formula: C18H19N3O
• Molecular Weight: 293.37 g/mol
• IUPAC Name: (RS)-1,2,3,9-Tetrahydro-9-methyl-3-[(2-methylphenyl)thio] -2H-carbazol-4-one hydrochloride
• Receptor Binding: It selectively binds to and blocks the 5-HT3 receptors, which are serotonin receptors located in the gastrointestinal tract and the central nervous system.
• Prevention of Nausea: By blocking these receptors, ondansetron prevents the action of serotonin, which is involved in triggering nausea and vomiting
• Chemotherapy: 8 mg administered intravenously (IV) or orally 30 minutes before chemotherapy, followed by additional doses if required.
• Postoperative: 4 mg IV administered just before or immediately after anesthesia.
• Radiation: 8 mg orally 1-2 hours before radiation therapy.
• Ondansetron hydrochloride is an effective medication for preventing and treating nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. By blocking serotonin receptors, it helps control these symptoms.