Atenlol

Description :

Applications
Atenolol is used alone or in combination with other medications to treat high blood pressure. It also is used to prevent angina (chest pain) and improve survival after a heart attack. Atenolol is in a class of medications called beta blockers.
Description
Atenolol is a second-generation beta-1-selective adrenergic antagonist that reduces heart rate and blood pressure and decreases myocardial contractility. It is FDA-approved and indicated in treating hypertension, angina pectoris, and acute myocardial infarction.
Preparation
Compound 3b (0.43 g, 1.7 mmol) in ethanol (5 cm3) and water (5 cm3) was heated under reflux with the platinum hydration catalyst 4 (1 mg, 2.3 × 10 -6 mol) for 72 h
Chemical Properties
Atenolol is a white to off-white crystalline powder with low solubility in water, known for its beta-blocking properties used in the treatment of hypertension and angina.
Definition
Atenolol is a selective beta-blocker medication used to manage hypertension, angina, and other cardiovascular conditions by slowing the heart rate and reducing the workload on the heart.