1,3-Phenylenediacetic Acid

Description :

In order to establish defined biomacromolecular systems for mineralised tissue applications, type I collagen was functionalised with 1,3-phenylenediacetic acid (Ph) and investigated at the molecular, macroscopic and functional levels. The solvothermal reactions of 1,2-bis(imidazol-1?-yl)ethane (bime), 1,3-phenylenediacetic acid, 1,4-phenylenediacetic acid), 1,2-phenylenediacetic acid with different metal ions gave rise to four novel helical coordination polymers.
Chemical Formula: C₁₁H₁₂O₄
Molecular Weight: Approximately 192.21 g/mol
Benzene Ring: A six-membered aromatic ring.
Carboxyl Groups (-COOH): Attached to the 1 and 3 positions of the benzene ring.
Melting Point: Around 200-205°C.
Appearance: Typically a white to off-white crystalline solid
Solubility: Soluble in organic solvents such as ethanol and slightly soluble in water.
Direct Carboxylation: Direct carboxylation of 1,3-dibromobenzene or other suitable derivatives with carbon dioxide in the presence of a base.
Esterification: The carboxyl groups can be converted into esters with alcohols.
Pharmaceutical Development: Its role as an intermediate can be critical in the synthesis of drugs with therapeutic properties.
1,3-Phenylenediacetic acid’s functional groups and aromatic structure make it versatile in various chemical and industrial applications. If you have specific questions or need more detailed information, feel free to ask!